Category: Kif4A
Dog Brucella Ab Test kit
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Brucellosis, also known as undulant fever, Mediterranean fever is a zoonosis and the infection is almost invariably transmitted by direct or indirect contact with infected animals or their products. Expansion of animal industries and urbanization, and the lack of hygienic measures in animal husbandry and in food handling partly account for brucellosis remaining a public…
Read MoreCovid-19 Antigen Rapid Tests (25 Tests)
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This test is authorized for non-prescription home use with self-collected anterior nasal (nares) swab samples from individuals aged 14 or older with symptoms of COVID-19 within the first 6 days of symptom onset. This test is also intended for non-prescription home use with adult-collected anterior nasal (nares) swab samples from individual aged 2 years or…
Read MoreMolecularly imprinted polymer as a synthetic antibody for the biorecognition of hazelnut Cor a 14-allergen
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Artificial receptors that mimic their natural biological counterparts have several advantages, such as lower production costs and increased shelf-life stability/versatility, while overcoming the ethical issues related to raising antibodies in animals. In this work, the proposed tailor-made molecularly imprinted polymer (MIP)-allergen receptors aimed at substituting or even transcending the performance of biological antibodies. For this purpose, a MIP…
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Direct Lymph Node Vaccination of Lentivector/Prostate-Specific Antigen is Safe and Generates Tissue-Specific Responses in Rhesus Macaques.
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Anti-cancer immunotherapy is rising from a nadir and demonstrating tangible advantages to sufferers. A wide range of approaches are actually employed. We’re invoking antigen (Ag)-specific responses via direct injections of recombinant lentivectors (LVs) that encode sequences for tumor-associated antigens into a number of lymph nodes to optimize immune presentation/stimulation. Right here we first exhibit the…
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Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant
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The D614G mutation within the Spike protein of the SARS-CoV-2 has successfully changed the early pandemic-causing variant. Utilizing pseudotyped lentivectors, we confirmed that the aspartate substitute by glycine in place 614 is markedly extra infectious. Molecular modelling means that the G614 mutation facilitates transition in the direction of an open state of the Spike protein. To…
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Highly efficient ‘hit-and-run’ genome editing with unconcentrated lentivectors carrying Vpr.Prot.Cas9 protein produced from RRE-containing transcripts
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The appliance of gene-editing know-how is presently restricted by the shortage of secure and environment friendly strategies to ship RNA-guided endonucleases to focus on cells. We engineered lentivirus-based nanoparticles to co-package the U6-sgRNA template and the CRISPR-associated protein 9 (Cas9) fused with a virion-targeted protein Vpr (Vpr.Prot.Cas9), for simultaneous supply to cells. Equal spatiotemporal management…
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